Ostarine, also known as MK-2866, is in class of drugs called SARMS, which stands for selective androgen receptor modulators.
Ostarine is selective in that it binds only to bone and muscle androgen receptors, which prevents things like prostate issues or hair loss or any of the other nasty side effects anabolic steroids can result in.
This experimental drug was developed in 2009 by the company Gtx in an effort to fight muscle wasting diseases. As with many bodybuilding drugs, osta accidentally turned out to be a fantastic side effect free tool for fitness enthusiasts, bodybuilders and those with nagging injuries they've given up hope of healing.
Ostarine is the most anabolic of any SARMS, making its first and foremost use for wanting to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the total gains will almost entirely be lean muscle.
Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories. One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue.
Recomping is where ostarine truly shines. The recomping effect of losing fat and gaining muscle at the same time is what the majority of users are looking for. Trying to achieve this when you are not absolutely new to training is extremely difficult.
The effects of ostarine translate to anabolism in bone and skeletal muscle tissue, which means it could be used in the future for a variety of uses, such as osteoporosis and as a concurrent treatment with drugs that reduce bone density. Therefore it has great application as a compound to use for rehabilitation of injuries, in particular bone and tendon related injuries.
As a SARM, Ostarine binds directly to the androgen receptors. While anabolic steroids also bind to androgen receptors, SARM's cannot convert to DHT or estrogen. Officially belonging to a group of drugs, Ligand, MK 2866's only purpose is direct anabolic activity. This SARM can be used for muscle growth or muscle preservation (diet dependent).
Ostarine, like anabolic steroids, will increase protein synthesis as well as nitrogen retention. However, unlike anabolic steroids, it will do so without any DHTor estrogen conversion.
While no direct estrogen conversion is present in terms of aromatase activity, mild increases in estrogen levels have been shown. This is perhaps why Ostarine has been shown to be good for joint health and healing. Estrogen often gets a bad wrap, but some is needed for good health and physical performance. It is,however, the direct binding to the receptor that is most important as it not only promotes anabolism, it alters the gene sequence directly at the receptor site; in fact, it is highly tissue specific, muscle and bone.
Recommended max dosage of Ostarine is around 25mg once a day for men, and 12.5mg for females. It has a 24 hour half-life.
Lowest recommended aesthetic dose (meaning for physique improvement) for males is 12.5mg. Lower doses will likely produce very little results to be notice in terms or muscle gains, but will help with join health.
Women's lowest recommended dose, for those seeking physique improvement, is 5mg a day, and it should be noted that therapeutic doses of as low as 3mg a day have been reported to be beneficial in both genders.
Benefits in bone and tendons have been reported at dosages as low as 12.5 mg per day.
While preserving muscle gains and decreasing calories, MK-2866 can help cut it off. Suggested dosing is 12.5-15mg for 4-6 weeks.
Shines best when used for gaining lean muscle (bulking) as it is the most anabolic of all the SARMS. Suggested dosage is 25 mg for 4-6 weeks. PCT is not necessary. An increase of 6 lbs. of lean, keepable gains can be observed during this period.
You can take Ostarine as high as 36 mg for 8 weeks BUT only if you weigh 210 lbs. Suppression is expected in higher doses so PCT after a cycle is a must.
Ostarine shines in recomping due to its nutrient portioning results. Calorie is used to build muscle which helps in weight loss and enhancing muscle mass and strength. Suggested dosing is 12.5-25 mg for 4-8 weeks.
Your diet must contain 30% of lean sources of protein to achieve the best recomp result.
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| Product Name | MK-2866 / Ostarine / Enobosarm | |
| Item | Specification | Result |
| Appearance | An odorless, almost white or white powder | pass |
| Identificaton | The retention time of the major peak is confirm to the RS | pass |
| Loss on Drying | Not more than 0.5% | 0.33% |
| Assay(HPLC) | Not less than 99.0% | 99.59% |
| Ignition residue | Not more than 0.1% | pass |
| Heavy metal | Not more than 20 ppm | pass |
1,High quality with competitive price:
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| AICAR | 2627-69-2 | acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown |
| MK2866 | 841205-47-8 | medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy. |
| MK-677 | 15972-10-0 | A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly |
| LGD-4033 | 1165910-22-4 | pharmacological profile similar to that of enobosarm, Ostarine,MK-2866 |
| GW501516 | 317318-70-0 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
| Andarine(S4) | 401900-40-0 | partial agonist, intended mainly for treatment of benign prostatic hypertrophy |
| SR9009 | 1379686-30-2 | under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice |
| SR9011 | 1379686-30-2 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
| RAD140 | 1182367-47-0 | New generation for gaining mass and cutting edges |
| YK11 | 366508-78-3 431579-34-9 |
a SARM and myostatin inhibitor in one |
| GHRP-2 | 158861-67-7 | Growth Hormone Releasing Peptide-2 |
| GHRP-6 | 87616-84-0 | Growth Hormone Releasing Peptide-6 |
| TB500 | 107761-42-2 | Thymosin beta 4 |
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